Lives listing by nationality: English
- Scurlock, Elizabeth [née Still] (died 1713), English home-maker
- S. E. (flourished c. 1735), English [unknown occupation]
- Seaman, Reverend William (born 1607–died 1680), English churchman, Orientalist, translator
- Seamer, James (born c. 1657–died 1739), English goldsmith, businessman, jeweller, banker, author
- Secker, Reverend Thomas, archbishop of Canterbury (born 1693–died 1768), English churchman
- Sedgwick, Reverend Adam (born 1785–died 1873), English geologist, university teacher, academician
- Sedgwick, Edward (flourished 1764), English lawyer, civil servant
- Seele, George (born c. 1728–died 1810), English schoolteacher, churchman
- Selwyn, George Augustus (born 1719–died 1791), English wit, politician
- Sergeant, John (born 1623–died before 1707), English churchman, Catholic, religious controversialist
- Serjeant, Cornelius (flourished 1692–1698), English [unknown occupation]
- Seward, Anna (born 1742–died 1809), English author, poet
- Seymour, Charles, 6th duke of Somerset (born 1662–died 1748), English aristocrat, courtier
- Seymour, Sir Edward (born 1633–died 1708), English politician, member of Parliament
- Seymour, Frances, duchess of Somerset [née Thynne] (born 1699–died 1754), English aristocrat, poet
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