Lives listing by nationality: English
- Sharpe, Samuel (born 1709–died 1778), English surgeon, academician
- Sharrock, Reverend Robert (born 1630–died 1684), English churchman, scientist, horticulturist, horticulturist
- Shaw, Thomas (born c. 1752–died c. 1830), English composer, violinist
- Shaw, William (born 1749–died 1831), English [unknown occupation]
- Sheffield, John, 1st duke of Buckingham (born 1647–died 1721), English politician, poet
- Sheffield, Katherine, duchess of Buckingham [née Darnley] (born c. 1681–died 1743), English aristocrat
- Shelley, Mary Wollstonecraft [née Godwin] (born 1797–died 1851), English author, novelist, biographer, travel-writer
- Shelley, Percy Bysshe (born 1792–died 1822), English author, poet
- Shelley, Sir Percy Florence, 3rd baronet (born 1819–died 1889), English aristocrat
- Shenderdine, Mr — (flourished c. 1816), English theatre employee
- Shenstone, William (born 1714–died 1763), English landscape gardener, poet, horticulturist
- Shenton, Richard (born c. 1730–died 1785), English churchman, singer
- Sherard, William (born 1659–died 1728), English botanist
- Sheridan, Charles Brinsley (born 1796–died 1843), English civil servant, poet
- Sheridan, Elizabeth Ann [née Linley] (born 1754–died 1792), English singer, author
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