Lives listing by occupation: politician
- Digges, William (born c. 1650–died 1697), American army officer, politician
- Dobbs, Arthur (born 1689–died 1765), Irish politician, landowner, colonial governor
- Dodington, George (born c. 1662–died 1720), English politician, civil servant, businessman, East India Company official
- Dodington, George Bubb, Baron Melcombe (born 1691–died 1762), English politician, member of Parliament, arts-patron, diarist, author
- Dolben, Sir Gilbert (born 1659–died 1722), English politician, member of Parliament, judge
- Donelson, Colonel John (born c. 1720–died 1785), American politician, civil servant, explorer, pioneer
- Donin de Champagneux, Luc Antoine (born 1744–died 1807), French politician, revolutionary, journalist
- Dornford, Doctor Josiah (born c. 1734–died 1810), English politician, civil servant, author
- Douglas, Alexander Hamilton, 10th duke of Hamilton (born 1767–died 1852), Scottish aristocrat, diplomat, politician, member of Parliament, academician
- Douglas, Archibald James Edward, 1st Baron Douglas of Douglas [née Stewart] (born 1748–died 1827), Scottish lawyer, politician, member of Parliament
- Douglas, Charles, 3rd duke of Queensberry (born 1698–died 1778), Scottish courtier, politician
- Douglas, Sylvester, Baron Glenbervie (born 1743–died 1823), Scottish lawyer, government minister, academician, politician, member of Parliament
- Dowdeswell, William (born 1721–died 1775), English politician, member of Parliament
- Drayton, William Henry (born 1742–died 1779), American colonist, plantation-owner, revolutionary, politician, army officer, soldier
- Drinker, Henry (born 1734–died 1809), American Quaker, merchant, speculator, politician
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