Lives listing by occupation: member of Parliament
- Savile, Sir George (born 1726–died 1784), English politician, member of Parliament
- Scheffer, Greve Ulric (born 1716–died 1799), Swedish army officer, diplomat, prime minister, politician, member of Parliament
- Scott, David (born 1746–died 1805), Scottish merchant, financier, East India Company official, politician, member of Parliament
- Scott, John, 1st earl of Eldon (born 1751–died 1838), English lawyer, politician, member of Parliament
- Scott, Sir William, Baron Stowell (born 1745–died 1836), English academic, lawyer, judge, politician, member of Parliament
- Scudamore, John, 1st Viscount Scudamore (born 1601–died 1671), English courtier, politician, member of Parliament, army officer, royalist
- Seymour, Sir Edward (born 1633–died 1708), English politician, member of Parliament
- Shaen, Sir James (died 1695), Irish politician, member of Parliament, civil servant, landowner, academician
- Sharp, Richard (born 1759–died 1835), English politician, member of Parliament, wit, academician
- Sheridan, Charles Francis (born 1750–died 1806), Irish politician, member of Parliament, author
- Simcoe, John Graves (born 1752–died 1806), English army officer, colonial administrator, politician, member of Parliament
- Sinclair, Sir John, 1st Baronet Sinclair of Ulbster (born 1754–died 1835), Scottish agriculturalist, politician, member of Parliament
- Skeffington, John, 2nd Viscount Massereene (born 1632–died 1695), English politician, member of Parliament, aristocrat
- Skene, Robert (born 1719–died 1787), Scottish army officer, soldier, politician, member of Parliament
- Smith, William (born 1756–died 1835), English politician, member of Parliament, Nonconformist
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