Lives listing by nationality: English
- Shipley, William (born 1715–died 1803), English painter, schoolteacher, educational founder, academy founder, commercial secretary, academician
- Shipley, Reverend William Davies (born 1745–died 1826), English churchman
- Shipman, Thomas (born 1632–died 1680), English militia officer, playwright
- Shore, Sir John, 1st Baron Teignmouth (born 1751–died 1834), English aristocrat, East India Company official, colonial governor, missionary
- Short, Thomas (born 1635–died 1685), English physician
- Shortgrave, Richard (died 1676), English scientific-instrument maker, academician, civil servant, surveyor
- Shower, Reverend John (born 1657–died 1715), English churchman, Nonconformist
- Shuckburgh, Doctor Richard (born 1728–died 1773), English physician, surgeon, civil servant
- Shute Barrington, John, 1st Viscount Barrington (born 1678–died 1734), English politician, speculator, author
- Sibbald, Sir James (died 1819), English East India Company official, merchant
- Siddons, William (born 1744–died 1808), English actor
- Sidney, Algernon (born 1622–died 1683), English [unknown occupation]
- Simcoe, John Graves (born 1752–died 1806), English army officer, colonial administrator, politician, member of Parliament
- Simpson, Doctor William (died 1680), English physician, alchemist
- Skeffington, John, 2nd Viscount Massereene (born 1632–died 1695), English politician, member of Parliament, aristocrat
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