Lives listing by nationality: English
- Oliver, John (flourished 1659–1660), English [unknown occupation]
- Oliver, Richard (born 1735–died 1784), English politician, member of Parliament, civic official
- Oliver, William (born 1695–died 1764), English physician, philanthropist
- Onslow, Arthur (born 1691–died 1768), English politician, member of Parliament
- Onslow, George, 1st earl of Onslow (born 1731–died 1814), English politician, member of Parliament
- Onslow, Thomas, 2nd Baron Onslow (born 1679–died 1740), English aristocrat, politician, member of Parliament, civil servant, landowner
- The Oracle (founded 1789), English newspaper
- Ord, Mary [née Scott] (flourished c. 1805), English home-maker
- Orde, Thomas (born 1746–died 1807), English politician, member of Parliament
- Ordnance, officers of the (appears in EE c. 1717), English government official
- Osbaldeston, Reverend Richard, bishop of London (born 1691–died 1764), English churchman, bishop
- Osborn, Mr — (flourished 1750–1775), English [unknown occupation]
- Osborne, Francis, 5th duke of Leeds (born 1751–died 1799), English aristocrat, government minister, politician, member of Parliament
- Osborne, Mary Godolphin, duchess of Leeds [née Godolphin] (born 1723–died 1764), English aristocrat
- Osborne, Peregrine, 2nd duke of Leeds (born 1659–died 1729), English naval officer
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