Lives listing by nationality: American
- Smith, Benjamin (flourished 1789), American private secretary
- Smith, Lieutenant Charles (flourished 1758), American army officer
- Smith, Charlotte [née Izard] (born 1770–died 1792), American home-maker
- Smith, George W. (born 1762–died 1811), American [unknown occupation]
- Smith, John (flourished 1759), American [unknown occupation]
- Smith, John Adams (born 1788–died 1854), American diplomat
- Smith, John R. (flourished 1850–1900), American merchant, mill-owner
- Smith, Nathaniel (flourished 1789), American civil servant, army officer
- Smith, P. (flourished 1686–1687), American [unknown occupation]
- Smith, Richard (flourished 1759–1761), American trader, guide, government agent, interpreter
- Smith, Samuel Stanhope (born 1751–died 1819), American churchman, university administrator
- Smith, Stanley M. (flourished 1879–1939), American soldier
- Smith, William (born 1728–died 1814), American merchant, politician
- Smith, Major William (born 1751–died 1837), American colonist, plantation-owner, army officer, politician
- Smith, William (born 1755–died 1816), American merchant
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