Lives listing by nationality: American
- Dyer, Eliphalet (born 1721–died 1807), American politician, lawyer
- Eddins, Samuel (died c. 1803), American [unknown occupation]
- Edes, Benjamin (born 1732–died 1803), American journalist, publisher, political agitator
- Edmond, William (born 1755–died 1838), American [unknown occupation]
- Edwards, Edward (born 1763–died 1845), American [unknown occupation]
- Edwards, Jonathan [the younger] (born 1745–died 1801), American churchman, Congregationalist
- Edwards, Pierpont (born 1750–died 1826), American lawyer, civil servant
- Edwards, Timothy (born 1738–died 1813), American [unknown occupation]
- Eichelberger, Martin (died c. 1840), American [unknown occupation]
- Eliot, Reverend Andrew (born 1718–died 1778), American churchman, Congregationalist
- Eliot, Samuel (born 1739–died 1820), American merchant, banker, philanthropist
- Ellery, William (born 1727–died 1820), American merchant, politician
- Ellicott, Andrew (born 1754–died 1820), American mathematician, astronomer, civil servant, surveyor
- Ellsworth, Abigail [née Wolcott] (born 1755–died 1818), American home-maker
- Ellsworth, Abigail (born 1774–died 1860), American home-maker
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