Lives listing with initial: S
- Sambuca, Antonio (died 1767), Italian author, historian
- Sancho, Ignatius (born 1729–died 1780), African slave, shopkeeper, author
- Sanderson, Reverend Robert, bishop of Lincoln (born 1587–died 1663), English churchman, theologian
- Sandherr, André (flourished c. 1773), French postal official
- Sandoz, Marie Frédérique Anne [née Bada] (born 1717–died 1792), Swiss salon hostess
- Sandoz, Montmollin Frères & Cie (active 1759–1767), Swiss trading firm
- Sandoz-Rollin, David Alphonse de (born 1740–died 1809), Swiss diplomat
- Sandoz de Rosières, François (born 1692–died 1779), Swiss aristocrat, politician
- Sandys, Reverend Edwin (born 1643–died 1705), English churchman
- Sanità, Magistrato de Venezia alla (founded c. 1400), Italian government department, health official
- San Martín, José de (born 1778–died 1850), Argentinian army officer, politician
- Le Sans-Culotte (founded 1794), French newspaper
- Sansom, John (flourished 1702–1717), English civil servant
- Sanson, Nicolas (born 1740–died 1789), French journalist, clerk
- Santaniello, Ferdinando (flourished 1698–1708), Italian university teacher, physician
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