Lives listing with initial: S
- Sharpe, Samuel (born 1709–died 1778), English surgeon, academician
- Sharrock, Reverend Robert (born 1630–died 1684), English churchman, scientist, horticulturist, horticulturist
- Shaw, Angus (died 1832), Canadian fur-trader, politician, tradesman
- Shaw, Benjamin (born 1752–died 1815), American [unknown occupation]
- Shaw, Elizabeth Smith (born 1750–died 1815), American home-maker
- Shaw, Thomas (born c. 1752–died c. 1830), English composer, violinist
- Shaw, William (born 1749–died 1831), English [unknown occupation]
- Shawe, Major — (flourished 1804), [unknown nationality & occupation]
- Sheafe, James (born 1755–died 1829), American [unknown occupation]
- Sheffield, John, 1st duke of Buckingham (born 1647–died 1721), English politician, poet
- Sheffield, Katherine, duchess of Buckingham [née Darnley] (born c. 1681–died 1743), English aristocrat
- Shelley, Mary Wollstonecraft [née Godwin] (born 1797–died 1851), English author, novelist, biographer, travel-writer
- Shelley, Percy Bysshe (born 1792–died 1822), English author, poet
- Shelley, Sir Percy Florence, 3rd baronet (born 1819–died 1889), English aristocrat
- Shenderdine, Mr — (flourished c. 1816), English theatre employee
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