Lives listing with initial: S
- Sewall, David (born 1735–died 1825), American lawyer, judge
- Sewall, Dummer (born 1737–died 1832), American [unknown occupation]
- Sewall, Henry (born 1752–died 1845), American [unknown occupation]
- Sewall, Stephen (born c. 1747–died 1799), American [unknown occupation]
- Seward, Anna (born 1742–died 1809), English author, poet
- Sewel, William (born 1653–died 1720), Dutch author, historian, translator, lexicographer
- Seyffer, Karl Felix von (born 1762–died 1822), German astronomer
- Seymour, Charles, 6th duke of Somerset (born 1662–died 1748), English aristocrat, courtier
- Seymour, Sir Edward (born 1633–died 1708), English politician, member of Parliament
- Seymour, Frances, duchess of Somerset [née Thynne] (born 1699–died 1754), English aristocrat, poet
- Seymour Conway, Francis, 1st marquess of Hertford (born 1718–died 1794), English aristocrat, courtier, politician, government minister
- Seymour Conway, Field Marshall Henry (born 1721–died 1795), English soldier, army officer, government minister
- Seytres, Joseph de, marquis de Caumont (born 1688–died 1745), French archaeologist, bibliophile, collector, collector, academician, historian
- Sèze, Romain de (born 1748–died 1828), French lawyer, academician
- Shackleton, Richard (born 1726–died 1792), Irish schoolteacher
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