Lives listing by nationality: English
- Chapman, Reverend Doctor Joseph (born c. 1743–died 1808), English academic, churchman, university administrator
- Chapone, Hester [née Mulso] (born 1727–died 1801), English journalist, educationalist, moralist
- Chapone, Sarah [née Kirkham] (born 1699–died 1764), English feminist, historian
- Chappell, Lucette (flourished 1789–1791), English home-maker
- Chappelow, Reverend Leonard (born 1744–died 1820), English academic, classicist, naturalist, author, poet
- Charles I, king of Great Britain and Ireland (born 1600–died 1649), English monarch
- Charles II, king of Great Britain and Ireland (born 1630–died 1685), English monarch
- Charleton, William (born 1642–died 1702), English collector, curator
- Charlett, Arthur (born 1655–died 1722), English university administrator
- Charters, Samuel (born 1742–died 1825), English East India Company official, colonial governor
- Chelsum, Reverend Doctor James (born c. 1740–died 1801), English churchman, academic
- Cheselden, William (born 1688–died 1752), English surgeon, anatomist
- Chesnel, Mary Sophia de, marquise de Chesnel de La Charbonnelaye [née Bentham] (born 1797–died 1865), English aristocrat
- Cheswell, Charles (flourished 1682–1700), English steward, estate manager
- Chetwode, Hester [née Brooking] (flourished 1700–1715), English gentlewoman
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