Lives listing by nationality: American
- Pierce, Joseph (born 1745–died 1828), American merchant, politician
- Pierce, William (born 1740–died 1789), American [unknown occupation]
- Pike, Nicholas (born 1743–died 1819), American schoolteacher, author
- Pike, William (born 1748–died 1804), American [unknown occupation]
- Pinckney, Charles (born 1757–died 1824), American lawyer, colonist, plantation-owner, politician
- Pinckney, Charles Cotesworth (born 1746–died 1825), American [unknown occupation]
- Pintard, Abigail [née Stockton] (born 1738–died 1817), American home-maker
- Pintard, John Marsden (died c. 1811), American [unknown occupation]
- Pitfield, Benjamin (died c. 1793), American grocer, tradesman
- Pittillo, James (flourished 1727–1760), American landowner
- The Pittsburgh Gazette (founded 1786), American newspaper
- Platt, Richard (born 1755–died 1830), American businessman, financier, army officer
- Pleasants, Thomas [junior] (born c. 1737–died 1804), American colonist, plantation-owner, merchant
- Plumb, William (born 1749–died 1843), American [unknown occupation]
- Plumer, William (born 1759–died 1850), American politician
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