Lives listing by nationality: American
- Dearborn, Henry (born 1751–died 1829), American [unknown occupation]
- Deblois, Gilbert [senior] (died c. 1791), American [unknown occupation]
- Delany, Sharp (born c. 1739–died 1799), American apothecary, politician
- Denney, William (flourished 1756–1759), American colonial administrator
- Dennis, Francis (born c. 1747–died 1812), American [unknown occupation]
- Dennis, Patrick (flourished 1789), American merchant, sea captain, civil servant
- Depriest, Tabitha (flourished 1767), American home-maker
- Depriest, William (died 1768), American counterfeiter
- Derby, Elias Hasket (born 1739–died 1799), American merchant
- Desaussure, Daniel (born 1736–died 1798), American merchant, politician
- Devens, Richard (born 1721–died 1807), American [unknown occupation]
- Dexter, Aaron (born 1750–died 1829), American [unknown occupation]
- Dexter, Samuel (born 1761–died 1816), American [unknown occupation]
- Dickinson, John (born 1732–died 1808), American lawyer, plantation-owner, pamphleteer, essayist, politician
- Digges, Dudley (born 1729–died 1790), American politician
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